A few genetic terms with a brief description ![]()
Alleles: Different versions of the same gene found at the same locus but in homologous chromosomes or in different individuals that may produce different phenotypes.
Allele frequency: The fraction of all the alleles of a gene in a population that are of one type.
Assortative mating: A mating scheme that relies on the pairing of unrelated individuals with similar phenotypes to obtain consistency of type and reinforce desirable traits
Codominant alleles: Two alleles that have different effects that are distinguishable in a heterozygous individual (ie; AB blood groups)
Cross-breeding: Crossing two different breeds
Dominant allele: One that determines the phenotype even when there is only one copy
Drift: Changes in allele frequencies over time due to chance as opposed to selection or mutation
Effective population size (Ne): The size of a hypothetical stable, randomly-mating population that would have the same rate of gene loss or increase in inbreeding as the real population (size N). As all finite populations are inbred to some degree and generally do not choose mates at random, Ne is typically 1/10 N or less, particularly if fewer males breed than females
Epistasis: Used to describe the situation where one gene's expression prevents the expression of another, ie; you cannot determine whether an albino would have had black or brown hair, though these two traits are controlled by separate genes
Fixation: Loss of all alleles of a gene but one
Founder: An individual drawn from a source population who contributes genetically to the derived subpopulation
Founder effect: Changes in allele frequencies that occur when a subpopulation is formed from a larger one. Typically many rare and usually undesirable alleles are excluded while a few carried by the founders get a big boost in frequency
Founder equivalents: The number of hypothetical founders that would have the same diversity as the descendant population. Generally much smaller than the actual number due to unequal use and allele loss (gene dropping)
Gene: That portion of the genome that carries the information for a single protein
Gene dropping: Loss of alleles due to genetic drift
Genetic bottleneck: When population numbers are temporarily reduced to a level insufficient to maintain the diversity in the population
Genetic diversity: Usually expressed in terms of percentage of genes that are polymorphic and/or are heterozygous
Genome: The total genetic makeup of an organism
Heritable: Passed on from parents to progeny through the chromosomes/DNA
Heritability: The fraction of the variability in a trait that is caused by genetic differences
Heterozygous: Carrying two different alleles of a gene
Heterozygous advantage: A situation where the heterozygous genotype for a particular gene shows the highest relative fitness
Heterozygous insufficiency: When the heterozygous genotype lacks sufficient gene product to have the normal phenotype. (Approximately equivalent to partial dominance)
Homologous chromosomes: In higher plants and animals, chromosomes are found in nearly identical "homologous" pairs, one coming from the sire and the other from the dam. A dog has 39 pairs, or 78 in total. Only one of each, chosen at random, is passed on through eggs or sperm to the progeny
Linebreeding: A scheme that attempts to maintain a high contribution of one or two ancestors through successive generations. Often used by breeders for any inbreeding less intensive than between first-degree relatives
Linkage: Measure of how frequently two genes found on the same chromosome remain together during gamete (egg or sperm) formation
Locus: The location of a gene on a chromosome
Monomorphic genes: Have only one common allele
Mutation: A change in the sequence of the base pairs in a DNA molecule
Mutation rate: The number of new mutations that occur per gene per gamete per generation
Outcrossing: Mating two individuals of the same breed that are sufficiently unrelated that the IC of the progeny is lower than the average of the parents
Polymorphic genes: Have 2 or more common alleles in the population
Recombination: The reciprocal exchange of portions of two homologous chromosomes (usually equivalent) during gamete formation
Recombinant frequency (RF): How often two linked genes are separated by recombination, generally expressed as a percentage of total progeny
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